Outpatient Methadone Maintenance Treatment Program
Listing of Alabama, alcoholism chemical dependency, treatment centers programs. Part of a United States directory of treatment centers programs organized by state. Methadone Wikipedia. Methadone. Clinical data. Outpatient Methadone Maintenance Treatment Program' title='Outpatient Methadone Maintenance Treatment Program' />Medical uses Methadone maintenance. Methadone is indicated for the maintenance treatment of opioid dependency i. MedPro Treatment Centers provides professionally supervised Opiate Addiction maintenance with the use of Methadone. Comfortable, compassionate and discreet. Outpatient Rehab Programs in all 50 states. Clicks to find all the Outpatient Rehabs in your state or city. The easiest resource on the web to find Outpatient Rehabs. Trade names. Dolophine, Methadose, others. AHFSDrugs. com. Monograph. Medline. Plusa. 68. Pregnancycategory. AU CUS C Risk not ruled outRoutes ofadministration. By mouth, intravenous, insufflation, sublingual, rectal. ATC code. Legal status. Legal status. Pharmacokinetic data. Bioavailability. 419. Protein binding. 859. Metabolism. Liver CYP3. A4, CYP2. B6 and CYP2. D6 mediated12Onset of action. Rapid3Biological half life. Duration of action. Single dose 48 h. Prolonged use Withdrawal prevention 12 days3 Pain relief 81. Excretion. Urine, faeces2IdentifiersRS 6 dimethylamino 4,4 diphenylheptan 3 one. CAS Number. Pub. Chem. CIDIUPHARBPSDrug. Bank. Chem. Spider. UNIIKEGGCh. EBICh. EMBLECHA Info. Card. Chemical and physical data. Formula. C2. 1H2. NOMolar mass. 30. D model JSmolChirality. Racemic mixture. CCCCC1CCCCC1C2CCCCC2CCNCCCOIn. Rohit Name Ringtone Download Mp3. Ch. I1. SC2. 1H2. NOc. 1 5 2. 02. H,5,1. H2,1 4. H3 YKey USSIQXCVUWKGNF UHFFFAOYSA N Y NY what is this verifyMethadone, sold under the brand name Dolophine, among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use. The effects last about six hours after a single dose. After long term use, in people with normal liver function, effects last 8 to 3. Methadone is usually taken by mouth and rarely by injection into a muscle or vein. Side effects are similar to those of other opioids. Commonly these include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and a decreased effort to breathe. Abnormal heart rhythms may also occur due to a prolonged QT interval. The number of deaths in the United States involving methadone poisoning declined to 3,3. Risks are greater with higher doses. Methadone is made by chemical synthesis and acts on opioid receptors. Methadone was developed in Germany around 1. Gustav Ehrhart and Max Bockmhl. It was approved for use in the United States in 1. Methadone is on the World Health Organizations List of Essential Medicines, the most effective and safe medicines needed in a health system. Globally in 2. 01. It is regulated similarly to other narcotic drugs. It is not particularly expensive in the United States. Medical useseditMethadone maintenanceeditMethadone is indicated for the maintenance treatment of opioid dependency i. Diagnostic and Statistical Manual of Mental Disorders DSM. A 2. 00. 9 Cochrane review found that methadone was effective in retaining people in treatment and in the reduction or cessation of heroin use as measured by self report and urinehair analysis but did not affect criminal activity or risk of death. The treatment of opioid dependent persons with methadone will follow one of two routes. MMT methadone maintenance therapy is prescribed to individuals who wish to abstain from illicit drug use but have failed to maintain abstinence from opioids for significant periods. The duration of methadone maintenance ranges from a few months to lifelong. Methadone reduction programs are suitable for addicted persons who wish to completely stop using drugs. The length of the reduction program will depend on the starting dose and speed of reduction, this varies between clinics and from person to person. In addition, enrollment in methadone maintenance has the potential to reduce the transmission of infectious diseases associated with opiate injection, such as hepatitis and HIV. The principal goals of methadone maintenance are to relieve opioid cravings, suppress the abstinence syndrome, and block the euphoric effects associated with opioids. However, methadone abuse does carry the potential for dependence. When used correctly, methadone maintenance has been found to be medically safe and non sedating, and provides a slow recovery from opioid addiction. It is also indicated for pregnant women addicted to opioids. Methadone is used as an analgesic in chronic pain. Due to its activity at the NMDA receptor, it may be more effective against neuropathic pain for the same reason, tolerance to the analgesic effects may be less than that of other opioids. People with long term pain will sometimes have to perform so called opioid rotation. Opioid rotation involves switching from one opioid to another, usually at intervals of between a few weeks, or more commonly, several months. Opioid rotation may allow for a lower equivalent dose, and hence fewer side effects may be encountered to achieve the desired effect. Then, over time, tolerance increases with the new opioid, requiring higher doses. This, in turn, increases the possibility of adverse reactions and toxicity. Then it is time to rotate again to another opioid. Such opioid rotation is standard practice for managing people with tolerance development. Usually when doing opioid rotation, one cannot go down to a completely naive dose, because there is cross tolerance carried over to the new opioid. However, methadone has a lower cross tolerance when switching to it from other opioids, than other opioids. This means that methadone can start at a comparatively lower dose than other opiates, and the time for the next switch will be longer. Opioid detoxificationeditMethadone is approved in the US, and many other parts of the world, for the treatment of opioid addiction. Its use for the treatment of addiction is usually strictly regulated. In the US, outpatient treatment programs must be certified by the Federal Substance Abuse and Mental Health Services Administration SAMHSA and registered by the Drug Enforcement Administration DEA in order to prescribe methadone for opioid addiction. Adverse effectsedit. Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 2. Street methadone was ranked 4th in dependence, 5th in physical harm, and 5th in social harm. On 2. 9 November 2. U. S. Food and Drug Administration issued a Public Health Advisory about methadone titled Methadone Use for Pain Control May Result in Death and Life Threatening Changes in Breathing and Heart Beat. The advisory said that the FDA has received reports of death and life threatening side effects in patients taking methadone. These deaths and life threatening side effects have occurred in patients newly starting methadone for pain control and in patients who have switched to methadone after being treated for pain with other strong opioid pain relievers. Methadone can cause slow or shallow breathing and dangerous changes in heartbeat that may not be felt by the patient. The advisory urged that physicians use caution when prescribing methadone to people who are not used to the drug and that people take the drug exactly as directed. Adverse effects of methadone include citation neededSedation. Diarrhea2. 3 or constipation2. Flushing2. 4Perspiration2. Heat intolerance. Dizziness2. 32. Weakness2. Chronic fatigue, sleepiness2. Sleep problems such as drowsiness,2. Insomnia,2. 42. Constricted pupils. Dry mouth2. 32. Nausea2. Low blood pressure.